Which Help should I choose? Normally we use HTML HELP (.chm) unless integrating into VS help or Windows help. - WinHelp (.hlp)
Deprecated. No longer ships with Windows OS (Vista and above). Move your authoring to HTML Help. A crippled WinHelp32.exe is still available for download. WinHelp is also the help system used for older versions of MSDN and VS, - HTML Help (.chm)
Use for all general application help. Also the help system used for older versions of MSDN and VS, - MS Help 2 (.HxS)
Use for Visual Studio 2002/2003/2005/2008 help integration. - AP Help (.H1S)
Use for Windows Vista OS/OEM system help. - Help Viewer (.mshc)
Use for Visual Studio 2010/2012/+ help integration. Also ships with Windows 8 OS (for Windows and OEM help).
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